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Researchers report in the journal Science Translational Medicine that a new method for encapsulating proteins allows them to be stored at high concentrations and administered to patients using regular syringes or an auto-injector.

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Sami Zarqa
Sami Zarqa
A professional journalist and writer, he has worked in the media and visual journalism field for over 20 years. During his career, he has covered various activities and events and prepared social, political, and cultural programs, starting from writing scripts and scenarios for episodes and programs, and ending with editing and preparing for broadcast. His experience and talent in the field of writing, research, and keeping up with everything new in the media and production fields have qualified him to write novels, television drama series, and poetry.

Dubai, United Arab Emirates – Researchers have developed a new technology that could allow rapid injection of drugs. These drugs require slow intravenous injection, such as those used to treat cancer and immune diseases.

The researchers said that there is new technology. This may allow rapid injection of medications that currently require slow intravenous injection.

Patients need a large amount of fluids.

This is when they are injected with antibody drugs, commonly used to treat cancer, autoimmune diseases and metabolic disorders.

This means that they must undergo intravenous injections that require a long time.

The reason is that antibodies, which are proteins, remain stable only in liquids with low concentrations. 

The researchers stated in the Journal of Translational Medicine Sciences that there is a new way to encapsulate proteins. This allows them to be stored in high concentrations and presented to patients using regular syringes or a self-injection device. 

The researchers coated the small particles with a substance they developed called (Money). 

In order for researchers to be able to place proteins in a liquid, they must maintain high concentrations. They also aim to preserve their stability and effectiveness.

The researchers confirm that the coated layer prevents particles from dissolving or sticking together in the liquid. Additionally, it keeps them dry and stable. 

“chocolate” wrapped in candy

“We came up with something like candy-coated chocolate, where the protein is inside, and our polymer forms a solid glass layer on the outside,” said study leader Eric Appel of Stanford University. 

The researchers were able to inject a solution at more than twice the concentration of usual injection fluids. 

This was in tests conducted using three different proteins: albumin, human immunoglobulin, and a monoclonal antibody to treat Covid.

“The new method will likely work with any biological drug, so we can easily inject it,” Abel said. 

“This takes those treatments from an ordeal that takes several hours in the clinic via intravenous injection, to something you can do in seconds,” he added.

He stressed that this can be used at home.

SorceReuters
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